HPLC Column, Axis C18, 5um, 4.6mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 59021‑15P Cogent Axis C18™ HPLC Column is a proven, legacy reversed‑phase C18 column, trusted by laboratories for consistent performance and method reliability across a wide range of analytical applications.
Built with a fully double end‑capped C18 bonded phase on high‑purity silica, this column minimizes secondary interactions and ensures reproducible retention and peak shape, making it ideal as a direct replacement or alternate in USP L1 methods.
✅ Widely used as a standard reference column for USP L1 applications
150 mm Length – High Resolution for Analytical Methods
Provides strong resolving power for complex mixtures
Improves separation of closely eluting analytes
Increases peak capacity for method development and validation
Ideal for routine QC and regulated workflows
✅ Selected when reliable resolution and reproducibility are required
4.6 mm ID – Standard Analytical Platform
Compatible with standard HPLC systems
Ideal for:
routine analytical testing
method validation and transfer
Typical Flow Rate Range
~0.8–1.5 mL/min
✅ Provides robust and consistent analytical performance
5 µm Particle – Balanced Performance & Low Backpressure
Provides:
Reliable efficiency for routine HPLC methods
Lower backpressure compared to smaller particle sizes
Long column lifetime
✅ Ideal for:
Routine QC and validated methods
Method transfer between laboratories
100 Å Pore Size – Standard Small Molecule Separations
Optimized for:
small molecule analysis
traditional reversed‑phase methods
Provides stable performance for:
hydrophobic compounds
neutral analytes
✅ Ensures consistent chromatography across standard applications
Why Choose Axis C18™ Columns
Proven Legacy Performance
Widely used in analytical laboratories for many years
Trusted for repeatability and consistency
USP L1 Compatibility
Fully suitable for USP L1 methods
Ideal for method validation and transfer
Reliable Selectivity
Traditional C18 retention characteristics
Predictable behavior across common reversed‑phase methods
✅ Preferred for routine methods requiring dependable performance
Application Performance Advantages
Suitable for:
Hydrophobic compounds
Neutral analytes
Long‑chain fatty acids
Provides:
Longer retention than C8 phases
Stable and reproducible separations
✅ Ideal for general‑purpose HPLC analysis
System & Sample Considerations
Compatible with standard HPLC systems
Suitable for routine and high‑throughput workflows
Recommended sample preparation:
👉 Use 0.2 µm syringe filters for proper sample preparation before injection
✅ Helps:
Prevent column fouling
Maintain long‑term performance and reproducibility
Typical Applications
USP L1 analytical methods
Pharmaceutical QC and validation
Routine HPLC analysis
Method development and transfer
Hydrophobic compound separations
Long‑chain fatty acid analysis
Important Usage Notes
Designed for standard analytical HPLC systems (4.6 mm ID)
Suitable for general reversed‑phase chromatography
Ideal for USP L1 method compatibility and reproducibility
Monitor system pressure according to instrument capability